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KIM DE LEENEER.
SENIOR COLLABORATOR

Phone +32(0)933 20 158
Mail kim.deleeneer@ugent.be
ORCID iD 0000-0002-9319-411X
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FIELD OF EXPERTISE

  • DNA Sequencing (Massive Parallel Sequencing, Sanger Sequencing)
  • MPS library preparations (Targeted/Whole Exome/Transcriptome Sequencing)
  • Data-Analysis
  • Screening Strategies

PROJECTS

Background
The next‐generation sequencing (NGS) revolution has paved the way to implement this technology in a clinical setting. The need for flexible, qualitative, and cost‐efficient workflows is high. As this is a constantly evolving and moving field, it is challenging to optimize and implement the newest state of the art technologies. Developing tailor made molecular tests for disorders is there for crucial to establish an efficient screening strategy. Several strategies have been explored, starting from PCR based screening strategy and moving to a hybridization based targeted panels for familial cancer syndromes. Our research includes exploring the different sequencing instruments and technologies (Minion up to Novaseq), library preps and bioinformatics tool to facilitate data analysis.
​Aim
Our main goal is to adapt and optimize these components to make it feasible to implement these analyses in a routine clinical setting.

DEGREES

  • ​Doctor of Medical Sciences, Defended June 2011 (dissertation: 'Genetic predisposition for breast cancer: Improved Molecular analyses')
  • ​Master in Biotechnology (Ghent University, 2006)
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  • Research
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    • Scientific News
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  • Contact